© 2007 National Science Teachers Association (NSTA). The Science Reflector, Summer 2007, Volume 36, Number 2. The North Carolina Science Teachers Association (NCSTA). In this investigation, students create an icosahedral virus model and consider how virus structure and behavior could be mimicked in nanotechnology applications. Students describe the structure of a virus, how viruses function as nanomachines, and how viruses self-replicate.